Head-to-head · computed 2026-08-11
ShedRx vs TMates
ShedRx: ShedRx advertises accessible entry pricing ($175 semaglutide, $199 tirzepatide) but tiers upward with dose — $249 and $289 respectively at the maintenance basis. TMates: TMates is a compounded GLP-1 telehealth service that includes medication and visits in one bundled monthly price. It offers both semaglutide and tirzepatide, with a 12-month plan that brings tirzepatide to $167/mo — the lowest committed-plan figure for tirz outside of bmiMD and NexLife.
Tirzepatide
| ShedRx | TMates | |
|---|---|---|
| All-in maintenance | $289/mo | $297/mo |
| Best plan rate | $289/mo | $167/mo |
| 12-month total | $3,468 | $2,004 |
| Status | Provider-stated · 2026-08-05 | Reported · 2026-07-14 |
The arithmetic
On the figures our desk holds, ShedRx's $289 a month undercuts TMates's $297 by $8 a month at the 10 mg/wk maintenance basis — $96 across a year. ShedRx's figure is provider-stated (captured 2026-08-05) and TMates's is reported (captured 2026-07-14); a status below 'verified' means our independent checkout capture is still pending, so treat the gap as the best current evidence rather than settled fact.
ShedRx's tirzepatide ladder runs $289 a month billed monthly. TMates's runs $297 a month billed monthly, and $167 a month on a twelve-month plan. On the twelve-month basis TMates's $2,004 beats ShedRx's $3,468 by $1,464 — with the winner's figure resting on a committed twelve-month plan, a structural difference that matters if you might stop early.
Semaglutide
| ShedRx | TMates | |
|---|---|---|
| All-in maintenance | $249/mo | $249/mo |
| Best plan rate | $249/mo | $158/mo |
| 12-month total | $2,988 | $1,896 |
| Status | Provider-stated · 2026-08-05 | Reported · 2026-07-14 |
The arithmetic
On monthly cost the two are tied at $249; the decision comes down to structure — ShedRx's (tiered by dose) against TMates's (structured titration; medication and provider visits included in price).
ShedRx's semaglutide ladder runs $249 a month billed monthly. TMates's runs $249 a month billed monthly, and $158 a month on a twelve-month plan. On the twelve-month basis TMates's $1,896 beats ShedRx's $2,988 by $1,092 — with the winner's figure resting on a committed twelve-month plan, a structural difference that matters if you might stop early.
Structure, side by side
ShedRx
- MembershipNone
- Dose policyTiered by dose
- CommitmentMonth-to-month
- CancellationCancel before renewal
- PharmacyPartner pharmacies
TMates
- MembershipNone
- Dose policyStructured titration; medication and provider visits included in price
- Commitment12-month plan or month-to-month; substantial difference in rates
- CancellationPer provider terms
- PharmacyPartner 503A pharmacy (not publicly named)
What our desk is watching on each
ShedRx: Start-vs-maintenance spread is among the widest in the index; budget on the maintenance figure.
TMates: The $158/mo (sema) and $167/mo (tirz) headline figures are 12-month plan rates; month-to-month is $249 (sema) and $297 (tirz) — some of the widest start-to-commitment spreads in the index. Reported status from RangeYourself 2026-07-14 verification.
Questions people ask
Is ShedRx or TMates cheaper in 2026?
The tirzepatide and semaglutide verdict blocks above give the computed answer at the maintenance basis, with the verification status of each figure; the short version is that whichever program's all-in monthly number is lower on this page is cheaper on the evidence we hold today, and both rows carry capture dates so you can judge freshness.
What does ShedRx vs TMates miss that checkout will show?
Taxes, state availability, current promotions, and any dose surcharge introduced after our capture date. Screenshot the order summary before paying — that capture, not any comparison page, is your contract.
Why do you compare at the maintenance dose instead of the starting dose?
Because starter pricing lasts one or two months and maintenance pricing lasts the rest of the year; comparing starts against maintenances is the single most common way GLP-1 comparisons mislead.
What do ShedRx and TMates cost over a full year of tirzepatide?
On the plans our database holds, a year of tirzepatide runs $3,468 at ShedRx and $2,004 at TMates — computed from each program's best published twelve-month route, with promotional figures labeled in the sections above and every number carrying its capture date.
Both records live in the normalized database; re-run the math yourself from the downloads. Full record pages: ShedRx · TMates. Official sites: ShedRx ↗ · TMates ↗. Nothing here is medical advice.